A study by a team from the University of Hong Kong has uncovered the anti-cancer properties of oleic acid. Scientists discovered that it stimulates the activity of specialized immune system cells—delta-gamma T cells—which are the first responders in the fight against infections and tumors.
The findings are based on experiments with human cell cultures treated with fatty acids. The first sample was treated with oleic acid, which is found in olive oil, nuts, avocados, and other foods, and the second sample was treated with palmitic acid, which is found in palm oil, meat, and dairy products.
Exposure to oleic acid enhanced T-cell function, while palmitic acid, conversely, reduced these anti-cancer properties by weakening T-cell function. Notably, analysis of patient blood samples confirmed that the levels of these fatty acids are associated with the results of cancer immunotherapy.
"This study shows for the first time that fatty acids in the diet can directly influence the effectiveness of our immune cells in fighting cancer," said study author Tu Wenwei.
He continues to study personalized nutritional strategies for cancer treatment and prevention. Currently, Wenwei recommends that cancer patients increase their intake of foods high in oleic acid and reduce their intake of processed fatty foods, which often contain palmitic acid.
Oleic acid is found in large quantities in vegetable oils, including sunflower, olive, almond, and others. Previously, scientists found that replacing butter with vegetable oil reduces the risk of cardiovascular disease.
