Scientists have presented an experimental treatment for various musculoskeletal disorders, from osteoporosis to spondylitis. They have discovered a peptide that regulates bone remodeling, restoring cellular balance.
A team from the University of Birmingham presented the results of research examining the peptide PEPITEM for bone restoration. According to the findings, PEPITEM enhances bone mineralization, formation, and density, and reverses bone loss.
PEPITEM offers clear advantages over existing drugs, such as bisphosphonates , which block osteoclast activity. The peptide does not impair the ability of osteoclasts to remove damaged bone tissue, but enhances the activity of bone-forming osteoblasts.
Working with human cell cultures, the scientists confirmed their findings and discovered that the peptide increases osteoblast activity, not their number. Further studies should confirm the treatment's potential and safety in humans.
