The influence of gut microbiota on overall health and various systems in particular is well known. A team of researchers from the Netherlands and Spain decided to study the direct impact of bacteria on muscle mass and function. To do this, they analyzed stool samples from healthy young adults and older adults over 65. Grip strength, leg press, and bench press, as well as maximal oxygen consumption during exercise, were used to assess physical fitness.
Analysis showed a positive effect of Roseburia bacteria on muscle mass and strength, Medical Express reports . For example, the presence of the R. inulinivorans strain increased grip strength by 29% or more. In experiments on mouse models, administration of R. inulinivorans also enhanced muscle function by approximately 30% and increased muscle fiber size.
Remarkably, in mice, the changes were accompanied by metabolic changes in proteins and enzymes that play a key role in energy production in muscles.
Scientists have discovered that older people have reduced levels of R. inulinivorans, so they are now exploring the potential of probiotics for treating age-related muscle loss. This hypothesis is currently being tested in preclinical experiments.
Previously, other scientists developed a technology for muscle tissue regeneration and growth in the face of severe deficits following severe injuries. The treatment is also planned for use in treating age-related muscle loss.
